From the north or the south along national route 3 and national route 281.
By plane:
There are domestic flights from Río Gallegos .
Distances from Puerto Deseado to:
Bariloche 1191 km
Buenos Aires 2099 km
Calafate 1044 km
Comodoro Rivadavia 285 km
Esquel 876 km
Los Antiguos 501 km
Neuquén 1370 km
Perito Moreno 421 km
Rawson 661 km
Río Gallegos 741 km
Río Grande 1519 km
Santa Rosa 1367 km
Viedma 1140 km
Ushuaia 1336 km