You can get to the Big Island of Chiloé by car following the carretera Panamericana Sur to Puerto Montt and then take a transshipping service to cross Canal de Chacao from the continent to the island, where you may travel and get to Castro, in the centre of the island. 
 
Distances from Castro to: 
 
Aysen 768 km 
Ancud 85 km 
Coihaique 414 km 
Chaitén 368 km 
Chile Chico 1181 km 
Cochrane 1126 km 
Frutillar 207 km 
Osorno 284 km 
Panguipulli 412 km 
Puerto Ibañez 892 km 
Puerto Natales 520 km 
Puerto Octay 229 km 
Puerto Porvenir 364 km 
Pucón 515 
Puerto Varas 195 km 
Puerto Montt 175 km 
Punta Arenas 2461 km 
Quellón 92 km 
Temuco 514 km 
Valdivia 391 km 
Villarrica 393 km